Binge Drinking Habit can Increase Risk for Ischemic Stroke in Korean Men
- Abstract
- Background and Purpose: Heavy alcohol consumption increases the risk for all strokes, whereas moderate regular alcohol consumption is associated with a lower risk for ischemic stroke. The effect of binge drinking on ischemic stroke has not been well known. We undertook a population-based case-control study and the purpose of this study was to evaluate the effect of the binge drinking on ischemic stroke risk.
Methods: Cases were recruited from patients aged 20 over and hospitalized due to first-ever ischemic stroke which was confirmed by diffusion-weighted MRI. Stroke-free controls, obtained from the database of the 4-5th Korean National Health and Nutrition Examination Survey, were matched with the cases by age, sex and education level. All participants completed an interview using a structured questionnaire about alcohol intake. A binge drinking pattern was defined as consuming 6 or more drinks (> 60g of pure alcohol) of the same alcoholic beverage in 1 session. We confined this analysis to male subjects and non-drinkers in past year and were excluded. A conditional logistic regression models were adjusted for age, hypertension, diabetes, coronary artery disease, hyperlipidemia, body mass index and smoking habit. The frequent drinking was defined as 4 times or more a week.
Results: Case (n=682) and control (n=1592) were included in this analysis. The binge drinking habit was found in 365 (53.5%) of the cases and 495 (31.1%) of the controls. Compared with non-binge drinkers, the odd ratio for ischemic stroke among binge drinkers was 2.96 (95% CI, 2.18-4.03) after adjusting the confounders. Compared with non-binge drinkers, the harmful association with ischemic stroke in occasional binge drinkers who drank less than 4 times a week (OR 2.31, 95%CI 1.61-3.31) and in frequent binge drinker who drank 4 times or more a week (OR 4.25, 95%CI 2.79-6.48).
Conclusions: This result suggests that a binge drinking habit may have a harmful effect on ischemic stroke.
- All Author(s)
- S. J. Lee
; J. G. Kim
; Y. Ko
; Y. J. Cho
; K. S. Hong
; J. M. Park
; K. Kang
; T. H. Park
; S. S. Park
; K. B. Lee
; D. H. Kim
; C. J. Kwan
; J. Lee
; J. T. Kim
; J. S. Lee
; M. K. Han
; H. J. Bae
- Issued Date
- 2016
- Type
- Article
- ISSN
- 0039-2499
- Citation Title
- Stroke
- Citation Volume
- 47
- Citation Number
- Suppl 1
- Language(ISO)
- eng
- DOI
- 10.1161/str.47.suppl_1.tp205
- URI
- http://schca-ir.schmc.ac.kr/handle/2022.oak/1023
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