장기간 메티마졸 사용 후 발생한 무과립구증과 연조직농양 1예
- Alternative Title
- A Case of Agranulocytosis and Soft Tissue Abscess after Increasing Methimazole Dose in a Patient with Graves Disease under Long-term Mainternance Therapy
- Abstract
- Antithyroid drugs (ATD) has been widely used to treat Graves' disease. However agranulocytosis, a serious fatal complication of ATD treatment, occurs in about 0.5 percent. The symptoms may mimic viral infections (fever, sore throat), and the potentially life-threatening pyogenic infections can go unrecognized initially. The median duration of drug exposure before the onset of acute agranulocytosis is within 30 days in most cases. We report a case of agranulocytosis with secondary soft tissue infection and abscess occuring after increasing the dose of methimazole in a woman who had taken methimazole for more than 10 years. We administered broad-spectrum antibiotics and aspirated the soft tissue abscess. A review of the medical literature regarding agranulocytosis in the setting of ATDs is presented.
- All Author(s)
- S. Y. Park
; S. W. Chun
; Y. J. Kim
; S. J. Kim
- Issued Date
- 2011
- Type
- Article
- Keyword
- Agranulocytosis; Graves' disease; Soft tissue infections
- Publisher
- 대한갑상선학회
- ISSN
- 2005-162X
- Citation Title
- Journal of Korean Thyroid Association
- Citation Volume
- 4
- Citation Number
- 1
- Citation Start Page
- 54
- Citation End Page
- 57
- Language(ISO)
- kor
- URI
- http://schca-ir.schmc.ac.kr/handle/2022.oak/1110
- 공개 및 라이선스
-
- 파일 목록
-
Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.