Concurrent Hemoperfusion and Hemodialysis in Patients with Acute Pesticide Intoxication
- Abstract
- BACKGROUND: Water soluble and insoluble chemicals in the pesticide formulation may be eliminated more effectively in time if hemodialysis (HD) and hemoperfusion (HP) are performed concurrently. AIM: This study is aimed at evaluating the efficacy of concurrent HP and HD in patients with acute pesticide intoxication. METHODS: Between January 2011 and December 2012, we used HP and HD consecutively (HP-HD group, 347 cases), and then during the next 2 years (January 2013 to December 2014), we used concurrent HP and HD (HPD group, 383 cases). We compared the clinical outcomes between the 2 groups. RESULTS: The mortality was higher in the HP-HD group than in the HPD group: (48.1 vs. 20.9%) for the overall mortality and (81.8 vs. 57.9%) for the paraquat (bipyridylium) mortality (p < 0.001). In multiple logistic analyses, age (p = 0.013), ingested volume (p < 0.001), and HP-HD (p = 0.014) were significant risk factors for mortality in the paraquat ingested group. CONCLUSION: Concurrent HP and HD would be an effective and safe treatment for patients with acute pesticide intoxication, in particular, paraquat intoxication.
- All Author(s)
- S. Park
; S. Lee
; H. Gil
; E. Lee
; J. Yang
; S. Hong
- Issued Date
- 2016
- Type
- Article
- Keyword
- Dialysis; Retrospective analysis; Clinical efficacy
- Publisher
- International Society of Hemofiltration
- ISSN
- 0253-5068
; 1421-9735
- Citation Title
- Blood Purification
- Citation Volume
- 42
- Citation Number
- 4
- Citation Start Page
- 329
- Citation End Page
- 336
- Language(ISO)
- eng
- DOI
- 10.1159/000451051
- URI
- http://schca-ir.schmc.ac.kr/handle/2022.oak/1566
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