Successful Early Rituximab Treatment in a Case of Systemic Lupus Erythematosus with Potentially Fatal Diffuse Alveolar Hemorrhage
- Abstract
- Diffuse alveolar hemorrhage (DAH) is a rare but devastating complication of systemic lupus erythematosus (SLE) with a high early mortality rate. DAH seldom occurs without active organ involvement. Recently, rituximab (RTX), a B cell-targeted therapy, has been reported to be effective for life-threatening autoimmune diseases. We describe a SLE patient who presented with acute respiratory failure due to DAH without other active organ involvement. This condition was dramatically improved with RTX without cyclophosphamide.© 2014 S. Karger AG, Basel
- All Author(s)
- J. O. Na
; S. H. Chang
; K.-H. Seo
; J. S. Choi
; H. S. Lee
; J. W. Lyu
; S.-S. Nah
- Issued Date
- 2015
- Type
- Article
- Keyword
- Systemic lupus erythematosus; Diffuse alveolar hemorrhage; Rituximab
- Publisher
- Karger
- ISSN
- 0025-7931
; 0368-9220
; 1423-0356
- Citation Title
- Respiration
- Citation Volume
- 89
- Citation Number
- 1
- Citation Start Page
- 62
- Citation End Page
- 65
- Language(ISO)
- eng
- DOI
- 10.1159/000369038
- URI
- http://schca-ir.schmc.ac.kr/handle/2022.oak/2086
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