LI-RADS v2017 categorisation of HCC using CT: Does moderate to severe fatty liver affect accuracy?
- Abstract
- OBJECTIVES: To compare the sensitivity of Liver Imaging Reporting and Data System (LI-RADS) v2017 for diagnosis of hepatocellular carcinoma (HCC) using multiphasic computed tomography (CT) between patients with and without moderate to severe fatty liver (MSFL). METHODS: This retrospective study included a total of 106 high-risk patients with 112 pathologically proven HCCs who underwent multiphasic CT. Patients were classified as MSFL (24 men, 2 women; mean age, 59.5 years [range, 38-79 years]) and non-MSFL (64 men, 16 women; mean age, 62.9 years [range, 40-89 years]) groups according to unenhanced CT liver and spleen parenchymal attenuation. Two independent radiologists assigned LI-RADS categories and accessed HCC features on CT. Sensitivities for LR-5 assignment and frequencies of HCC features were compared between the two groups. RESULTS: Sensitivities of LR-5 assignment for diagnosing HCCs were not significantly different between MSFL and non-MSFL groups (65.4% [17/26] vs. 76.7% [66/86] for reviewer 1, p = 0.247; 73.1% [19/26] vs. 76.74% [66/86] for reviewer 2, p = 0.702). No significant differences in the frequencies of arterial hyperenhancement, washout, and capsule were observed between the two groups (96.2% [25/26] vs. 98.8% [85/86], p = 0.412; 80.8% [21/26] vs. 89.5% [77/86], p = 0.308; and 53.8% [14/26] vs. 57% [49/86], p = 0.778, respectively). CONCLUSIONS: LI-RADS v2017 using CT showed comparable sensitivity for diagnosing HCC regardless of MSFL. KEY POINTS: • Using LI-RADS v2017 with CT, diagnosis of HCC in patients with MSFL showed similar sensitivity to that in patients without MSFL. • Frequencies of major HCC features (arterial hyperenhancement, washout, and capsule) on CT between the MSFL and non-MSFL groups were not significantly different. • LI-RADS using CT may be feasible for diagnosing HCC in patients with fatty liver.
- All Author(s)
- S. S. Kim
; J. A. Hwang
; H. C. Shin
; S. Y. Choi
; T. W. Kang
; S. S. Jou
; W. H. Lee
; S. Park
; N. H. Heo
- Issued Date
- 2019
- Type
- Article
- Keyword
- Carcinoma, hepatocellular; Fatty liver; Multidetector computed tomography; Liver neoplasms
- Publisher
- European Association of Radiology
European Society of Radiology
European Congress of Radiology
- ISSN
- 0938-7994
- Citation Title
- European Radiology
- Citation Volume
- 29
- Citation Number
- 1
- Citation Start Page
- 186
- Citation End Page
- 194
- Language(ISO)
- eng
- DOI
- 10.1007/s00330-018-5657-y
- URI
- http://schca-ir.schmc.ac.kr/handle/2022.oak/2645
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