보상성 다한증에서 20% Aluminum Chloride Hexahydrate의 효과

Abstract

Background: Compensatory hyperhidrosis is the most common complication after thoracoscopic sympathetic operation in hyperhidrosis. It is not only decrease patient`s satisfaction but also gives another burdens to the patients. Unfortunately remarkable treatment for compensatory hyperhidrosis does not exist yet. The purpose of this study was to evaluate the effect of decreased sweating production using 20% aluminum chloride hexahydrate on compensatory hyperhidrosis. Material and Method: From May to July, 2000, 8 patients were evaluated. All of them complained of severe discomfort due to compensatory hyperhidrosis. Degree of compensatory sweating was subjectively assessed thorough questionnaire as follows: 1=absent, 2=mild, 3=moderate 4=severe, 5=disabling, Also degree of life satisfaction was subjectively assessed thorough questionnaire as follows: 1=Absolutely no satisfaction, 2= ≤25%, 3=<25-≤50%, 4=<50-≤75%, 5=<75-≤100%. Numerical changes before and after applying of 20% Aluminum Chloride Hexahydrate were compared and analyzed using the Wilcoxon signed rank test. Result: Degree of compensatory sweating was 4.25±0.46 before treatment and 2.75±1.07 after treatment(p=0.01). Also, patients` satisfaction degree was 1.25±0.46 before treatment and 4.00±1.07 after treatment(p=0.011). Conclusion: Our findings demonstrated that symptom improvement and life satisfaction increased using 20% Aluminum Chloride Hexahydrate in compensatory hyperhidrosis. However further evaluation and long term follow up are needed in many more paitents.