A new method of EMR: submucosal injection of a fibrinogen mixture
- Abstract
- Background
The technical limitation associated with submucosal injection of normal saline solution during EMR is the relatively short duration of mucosal elevation. The clinical application of a new method of EMR with submucosal injection of a fibrinogen mixture was evaluated.
Methods
Thirty-five early stage neoplastic gastric lesions were resected by EMR with submucosal injection of a fibrinogen mixture. The efficacy and clinical outcomes were analyzed.
Results
Additional submucosal injection was not required for any of the 35 lesions to complete the EMR with submucosal injection of a fibrinogen mixture procedure. The rates of en bloc resection and complete resection were, respectively, 82.9% and 88.6%. The en bloc resection rate was significantly lower for lesions over 20 mm in diameter (60% vs. 92%; p<0.05) and for lesions on the lesser curvature or posterior wall of the stomach compared with those on the greater curvature or anterior wall (55.6% vs. 92.3%; p<0.05). The rate of complete resection also was dependent on the size and location of the lesions. There was no major EMR with submucosal injection of a fibrinogen mixture related complication including bleeding or perforation.
Conclusions
EMR with submucosal injection of a fibrinogen mixture is an easy, safe, and technically efficient method for complete EMR.
- All Author(s)
- S.-H. Lee
; W.-Y. Cho
; H.-J. Kim
; Y.-H. Kim
; I.-K. Chung
; H.-S. Kim
; S.-H. Park
; S.-J. Kim
- Issued Date
- 2004
- Type
- Article
- Publisher
- American Society for Gastrointestinal Endoscopy
- ISSN
- 0016-5107
- Citation Title
- Gastrointestinal Endoscopy
- Citation Volume
- 59
- Citation Number
- 2
- Citation Start Page
- 220
- Citation End Page
- 224
- Language(ISO)
- eng
- DOI
- 10.1016/S0016-5107(03)02689-0
- URI
- http://schca-ir.schmc.ac.kr/handle/2022.oak/2801
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