Erythropoietin 항체에 의해 유발된 진성 적혈구 무형성증 (Pure Red-cell Aplasia) 1예
- Alternative Title
- Pure Red-Cell Aplasia Due to Antibodies Against Erythropoietin
- Abstract
- Recombinant human erythropoietin (rHuEPO) is extensively used in anemic patients on dialysis. We experienced a case of pure red-cell aplasia (PRCA) caused by anti-rHuEPO Antibody. A 48-year-old male with CRF was placed on chronic hemodialysis. He developed severe anemia (Hb 6.6 g/dL) without any apparent blood loss. A transfusion was given and the rHuEPO dose was increased to 12, 000 U/week SC. A bone marrow study was carried out. Anti-rHuEPO antibodies were positive. rHuEPO therapy was stopped. No improvement in the anemia was apparent. Although very rare, anti-rHuEPO antibodies should be evaluated in patients with severe anemia without obvious etiology.
- All Author(s)
- J. O. Yang
; H. W. Gil
; S. H. Kwon
; Y. J. Choi
; E. Y. Lee
; S. Y. Hong
- Issued Date
- 2004
- Type
- Article
- Keyword
- Erythropoietin antibody; Pure red- cell aplasia; Anemia
- Publisher
- 대한신장학회
The Korean Society of Nephrology
- ISSN
- 1225-0015
; 1975-9460
; 2211-9132
; 2211-9140
- Citation Title
- 대한신장학회지
Korean Journal of Nephrology
- Citation Volume
- 23
- Citation Number
- 3
- Citation Start Page
- 528
- Citation End Page
- 531
- Language(ISO)
- kor
- URI
- http://schca-ir.schmc.ac.kr/handle/2022.oak/2869
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