Isotretinoin 투여로 호전을 보인 전신성 환상 육아종 1예

Abstract

Generalized granuloma annulare (GGA) is an uncommon type of granuloma annulare. It is frequently characterized by chronicity and unresponsiveness to a number of therapeutic modalities. A variety of systemic treatment modalities for GGA have been tried, including PUVA, dapsone, hydroxychloroquine, systemic corticosteroids, niacinamide, vitamin E and chlorambucil. However, their efficacy was not very encouraging. We present a case of GGA which showed a satisfactory response to isotretinoin. To conclude, isotretinoin may be considered as treatment for GGA in patients with unacceptable cosmetic disfigurements or symptoms.