고용량의 Potassium Iodide ( KI ) 로 치료한 Panniculitis 양상의 Sweet 증후군 1 예

Abstract

Sweets syndrome, first described in 1964 by Sweet, is characterized by fever, neutrophilic leukocytosis, sudden onset of asymmetric, erythematous, often painful skin lesions, and dense dermal infiltrates of mature neutrophils without signs of vasculitis. The disease responds rapidly to systemic therapy with corticosteroids but recurs in about 25% of the cases. Alternative treatments include potassium iodide, colchine, dapsane. clofazimine, cyclosporin. We report a case of classic sweet`s syndrome which was successfully treated with potassium iodide without adverse reactions. 33 year-old male patient became afebrile and symptom free within 24h after starting potassium iodide 900㎎/day. The cutaneous eruptions subsided completely in 5 days. He received the drug only for 12days. but there has been no recurrence after 6 months under observation.