전신 PUVA로 치료한 Wells 증후군 1 예

Abstract

Wells' syndrome, or eosinophilic cellulitis, is characterized by recurrent cutaneous swellings which resemble acute bacterial cellulitis, and by distinctive histopathological changes. Skin lesions show dermal eosinophilic infiltration and the characteristic 'flame figures', but not pathognomonic, which are composed of eosinophil major protein deposited on collagen bundles. A 51-year-old woman developed a chronic, pruritic, erythematous to dark-brown colored, annular, infiltrated plaques with papules, vesicles and some crusts on the chest, abdomen, back and both forearms with the clinical and histological features of Wells' syndrome. Skin lesions had recurred frequently with systemic corticosteroids therapy, so we tried systemic PUVA and treated her successfully without recurrence until now.