염증성장질환 환자에서의 장관 외 피부 증상: 설문조사 연구 및 문헌 고찰
- Alternative Title
- Extraintestinal Cutaneous Manifestations in Inflammatory Bowel Disease: Survey and Literature Review
- Abstract
- Background: Inflammatory bowel disease (IBD) is a chronic, relapsing, inflammatory disease of the gastrointestinal tract. IBD tends to coincide with several cutaneous symptoms and signs; previous studies have suggested a link between IBD and immune-mediated skin diseases (ISDs) such as psoriasis, rosacea, and atopic dermatitis. However, there is a paucity of reports on extraintestinal cutaneous manifestations in patients with IBD from Asia and Korea. Objective: We examined the prevalence of cutaneous manifestations in IBD patients and investigated the possible association between IBD and various dermatoses in a Korean tertiary care hospital.
Methods: Detailed questionnaires were administered to 120 patients diagnosed with IBD treated at the gastrointestinal center of our hospital. We also extracted their medical records retrospectively to obtain additional information about both their cutaneous manifestations and IBD, including disease duration and treatment course. A literature review on the prevalence of psoriasis in IBD patients was performed to clarify the association between those diseases.
Results: Crohn’s disease and ulcerative colitis were noted in 58 and 62 cases, respectively. Reactive skin lesions including aphthous stomatitis, erythema nodosum, and pyoderma gangrenosum were found in 12 cases (10%). ISDs such as psoriasis, rosacea, and atopic dermatitis were present in 3.3%, 21.7%, and 12.5% of cases, respectively. Other dermatoses including herpes zoster, xerosis, and skin fungal infection were also detected.
Conclusion: The prevalence of cutaneous manifestations in IBD is similar to that reported previously in Asian patients. Future investigations on the associations between skin diseases and IBD are needed to understand the pathogenesis and immunologic background of their comorbidities.
- All Author(s)
- S. M. Lee
; S. Y. Lee
; J. S. Lee
; M. K. Cho
; S. H. Lee
; Y. H. Jung
; J. E. Kim
- Issued Date
- 2020
- Type
- Article
- Keyword
- Colitis ulcerative; Crohn disease; Inflammatory bowel diseases; Inflammatory skin diseases
- Publisher
- 대한피부과학회
Korean Dermatological Association
- ISSN
- 0494-4739
; 2713-7627
- Citation Title
- 대한피부과학회지
Korean Journal of Dermatology
- Citation Volume
- 58
- Citation Number
- 2
- Citation Start Page
- 77
- Citation End Page
- 85
- Language(ISO)
- kor
- URI
- http://schca-ir.schmc.ac.kr/handle/2022.oak/3132
- 공개 및 라이선스
-
- 파일 목록
-
Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.