Clinical Outcomes After Drug-Coated Balloon Treatment in Popliteal Artery Disease: K-POP Registry 12-Month Results
- Abstract
- Background and objectives: The popliteal artery is generally regarded as a "no-stent zone". Limited data are available on the outcomes of drug-coated balloons (DCBs) for popliteal artery disease. This study aimed to evaluate the 12-month clinical outcomes among patients who received DCB treatment for atherosclerotic popliteal artery disease.
Methods: This prospective, multicenter registry study enrolled 100 patients from 7 Korean endovascular centers who underwent endovascular therapy using IN.PACT DCB (Medtronic) for symptomatic atherosclerotic popliteal artery disease. The primary endpoint was 12-month clinical primary patency and the secondary endpoint was clinically driven target lesion revascularization (TLR)-free rate.
Results: The mean age of the study cohort was 65.7±10.8 years, and 77% of enrolled patients were men. The mean lesion length was 93.7±53.7 mm, and total occlusions were present in 45% of patients. Technical success was achieved in all patients. Combined atherectomy was performed in 17% and provisional stenting was required in 11%. Out of the enrolled patients, 91 patients completed the 12-month follow-up. Clinical primary patency and TLR-free survival rates at 12 months were 76.0% and 87.2%, respectively. A multivariate Cox regression analysis identified female and longer lesion length as the significant independent predictors of loss of patency.
Conclusions: DCB treatment yielded favorable 12-month clinical primary patency and TLR-free survival outcomes in patients with popliteal artery disease.
Trial registration: ClinicalTrials.gov Identifier: NCT02698345.
- All Author(s)
- Jong-Il Park
; Young-Guk Ko
; Seung-Jun Lee
; Chul-Min Ahn
; Seung-Woon Rha
; Cheol-Woong Yu
; Jong Kwan Park
; Sang-Ho Park
; Jae-Hwan Lee
; Su-Hong Kim
; Yong-Joon Lee
; Sung-Jin Hong
; Jung-Sun Kim
; Byeong-Keuk Kim
; Myeong-Ki Hong
; Donghoon Choi
- Issued Date
- 2024
- Type
- Article
- Keyword
- Angioplasty; Atherosclerosis; Popliteal artery
- Publisher
- 대한순환기학회
대한심장학회
The Korean Society of Circulation
Korean Society of Cardiology
- ISSN
- 1738-5520
; 1738-5555
- Citation Title
- Korean circulation journal
- Language(ISO)
- eng
- DOI
- 10.4070/kcj.2024.0006
- URI
- http://schca-ir.schmc.ac.kr/handle/2022.oak/3465
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