다중 역전사 중합연쇄반응으로 증명된 급성 바이러스성 하기도 감염 양상
- Alternative Title
- Viral Etiologic Agents in Acute Viral Lower Respiratory Tract Detected by Multiplex RT-PCR
- Abstract
- Purpose : This study was performed to examine seasonal occurrences of respiratory viruses and detect viral etiologic agents, by multiplex RT-PCR in children with acute lower respiratory tract infection (ALRI). Methods : Nasopharyngeal aspirates (NPA) were collected from 654 hospitalized children with ALRI on admission at Soonchunhyang University Cheonan Hospital and analysed by multiplex RT-PCR between January 2005 and December 2005. Results : Viral agents were detected from 234 subjects (35.8%). The identified viral pathogens were respiratory syncytial virus (RSV) (34.2%), adenovirus (33.8%), parainfluenza virus (21.8%), influenza virus type A (8.1%) and influenza virus type B (2.1%). Viral ALRI occurred most frenquently during the 1st year of life. Clinical diagnoses of viral ALRI included pneumonia (72.2%), bronchiolitis (14.5%), tracheobronchitis (9.8%) and croup (3.5%). The most common cause of bronchiolitis was RSV. Common clinical symptoms and signs of viral ALRI were cough (93.4%), fever (78.2%), rhinorrhea (72.5%), rale (60.2%), and wheezing (26.2%). Conclusion : Viral agents were detected by multiplex RT-PCR in 35.8% of NPA obtained from 654 hospitalized patients with acute respiratory tract infections. Multiplex RT-PCR may be useful for detecting virus in children.
- All Author(s)
- 정희영
; 이정호
; 김용배
; 남해선
; 최영진
; 김창진
; 박준수
- Issued Date
- 2007
- Type
- Article
- Keyword
- Viral Etiologic Agents in Acute Viral Lower Respiratory Tract Detected by Multiplex RT-PCR
- Publisher
- 대한 소아알레르기 호흡기학회
- ISSN
- 1225-679x
; 1226-8739
- Citation Title
- 소아알레르기 호흡기학회지
Pediatric Allergy and Respiratory Disease
- Citation Volume
- 17
- Citation Number
- 4
- Citation Start Page
- 344
- Citation End Page
- 353
- Language(ISO)
- kor
- URI
- http://schca-ir.schmc.ac.kr//handle/2022.oak/424
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