대장내시경 시행시 항콜린제 사용의 유용성
- Alternative Title
- A Clinical Usefulness of Premedication with Hyoscine N-butyl Bromide in Colonoscopy
- Abstract
- Background/Aims:
We conducted a prospective, randomized, double-blinded, placebo-controlled trial to investigate the effect of hyoscine-N-butyl bromide during colonoscopy.
Methods:
A total of 133 patients undergoing colonoscopy were randomized to receive either 20 mg of hyoscine-N-butyl bromide (n=70) or normal saline solution (n=63) via intramuscular injection as premedication.
Results:
The mean cecal intubation time and withdrawal time in the hyoscine- N-butyl bromide group were significantly shorter than those of the control group (5.26±2.78 min vs. 6.74±4.89 min; p=0.032, 5.42±1.54 min vs. 6.18±2.54 min; p=0.038, each). The spasm grade in the hyoscine-N-butyl bromide group was significantly lower than that of the control group (p<0.001). No significant differences were found in the polyp detection rate (15.7% vs. 28.6%; p=0.073) and adenoma detection rate (10.0% vs. 15.9%; p=0.311). Difficulty of colonoscopy for the endoscopists and nurses (p=0.853; p=0.732), the patient's comfort (p=0.891) and the patient's willingness to repeat colonoscopy (85.7% vs. 82.5%; p=0.932) were also similar in both groups.
Conclusions:
Premedication with intramuscularly administered hyoscine-N-butyl bromide do not demonstrate any additional benefits except reducing the colonoscopy insertion time.
- All Author(s)
- 김은옥
; 이석호
; 김덕수
; 이창균
; 이태훈
; 정일권
; 박상흠
; 김선주
- Issued Date
- 2010
- Type
- Article
- ISSN
- 2234-2400
; 2234-2443
- Citation Title
- The Korean Journal of Gastrointestinal Endoscopy
- Citation Volume
- 41
- Citation Number
- 1
- Citation Start Page
- 10
- Citation End Page
- 15
- Language(ISO)
- kor
- URI
- http://schca-ir.schmc.ac.kr//handle/2022.oak/431
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