살충제 중독환자에서 혈액관류가 혈중 살충제 농도에 미치는 영향
- Alternative Title
- The Effect of Hemoperfusion on Plasma Concentration of Toxins in Acute Pesticide Poisoned Patients
- Abstract
- Purpose: Hemoperfusion is an effective modality of extracorporeal elimination of toxins in acutely poisoned patients. We evaluated the effect of hemoperfusion on plasma concentration of toxins in patients exposed to certain pesticides. Methods: Eleven patients who were acutely exposed to pesticides participated in our study. We measured plasma pesticide concentration from the whole blood obtained by arterial and venous sources by gas chromatography. Results: The plasma concentrations of only 3 patients was measured. Methidation clearance by hemoperfusion was 82.2%, fenitrothion was 23%, and endosulfan was 0% Conclusion: Measurement of plasma organophosphate concentration is not a practical application. Our results suggest that hemoperfusion is applicable in patients with pesticide intoxication according to clinical status.
- All Author(s)
- 길효욱
; 양종오
; 이은영
; 홍세용
- Issued Date
- 2006
- Type
- Article
- Keyword
- Hemoperfusion; Organophosphourus compounds; Pesticides poisoning
- Publisher
- 대한임상독성학회
- ISSN
- 1738-1320
- Citation Title
- 대한임상독성학회지
Journal of the Korean Society of Clinical Toxicology
- Citation Volume
- 4
- Citation Number
- 1
- Citation Start Page
- 1
- Citation End Page
- 6
- Language(ISO)
- kor
- URI
- http://schca-ir.schmc.ac.kr/handle/2022.oak/464
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