우리나라 일개 병원 암 환자에서 중심정맥관 합병증에 관한 후향적 조사
- Alternative Title
- Retrospective Analysis for Complications of the Central Venous Catheter in Patients with Cancer at a Single Center in Korea
- Abstract
- Purpose: A central venous catheterization (CVC) is frequently used for delivering anti-cancer chemotherapeutic agents, blood products, parenteral nutrition, and other intravenous therapy in patients with cancer. Major complications of CVC use are thrombosis, infection, and mechanical complications. The aim of this study was to evaluate the frequency of CVC complications and related factors. Methods: The records of cancer patients who received a CVC at our university hospital from March 2001 to October 2006 were retrospectively investigated. Chi square test was used to determine whether there was a related factor for thrombosis or infection, and Kaplan-Meier analysis for univariate analysis, or Cox-regression analysis for multivariate analysis was used for catheter life span. Results: Three hundred and ten CVCs (235 nontunneled, 75 tunneled) were inserted in 310 patients (157 males, 153 females). Among them, 104 had hematologic cancers and 206 had solid cancers. The mean age of the patients was 52 years (range, 19~82 years). CVC complications occurred in 60 cases (19%). CVC-related thrombosis occurred frequently in patients with infection (P=0.003), whereas diagnosis, catheter type, transfusion, and TPN history did not affect infection or thrombosis. The mean duration of the catheter was 102 days (range, 2~1,330 days), and the duration was prolonged in patients with tunneled catheters (P=0.000), or without transfusion through CVC (P=0.030). Conclusion: The major complications for long-term use of a CVC were infectionand thrombosis. Tunneled catheter was effective tool for long term use, especially in cases without transfusion through CVC. The studies on the prevention or treatment ofthrombosis and infection are, therefore, warranted by using CVC for an extended period of time.
- All Author(s)
- 김은정
; 김현정
; 김한조
; 김경하
; 김세형
; 이상철
; 배상병
; 김찬규
; 이남수
; 이규택
; 박성규
; 원종호
; 박희숙
; 홍대식
- Issued Date
- 2010
- Type
- Article
- Keyword
- Catheterization; Central venous; Hematologic neoplasms/complications; Neoplasms
- Publisher
- 한국호스피스완화의료학회
- ISSN
- 1229-1285
; 2287-6189
; 2765-3072
- Citation Title
- 한국호스피스완화의료학회지
Journal of Hospice and Palliative Care
- Citation Volume
- 13
- Citation Number
- 1
- Citation Start Page
- 24
- Citation End Page
- 31
- Language(ISO)
- kor
- DOI
- 10.14475/kjhpc.2010.13.1.24
- URI
- http://schca-ir.schmc.ac.kr/handle/2022.oak/504
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