투석 및 관류에 의한 살충제 포스파미돈의 제거 효율
- Alternative Title
- Effect of Dialysis and Perfusion on Phosphamidon in vitro
- Abstract
- Purfose: This study was to observe the phosphamidon reduction rate after haemoperfusion (HP) and Hemodialysis (HD) in vitro. Methods: We started off by measuring the clearance of HD and HP for the phosphamidon in vitro. Phosphamidon was measured hourly by High-pressure liquid chromatography. Results: Phosphamidon clearance was effectiveness in HP and HD. Phosphamidon reduction rate was no difference between HD and HP; $64\%$ versus $91.\%1$ at starting, $82.2\%$ versus $80.2\%$ at 1 hours, $82.2\%$ versus $73.8\%$ at 2 hours, $34.4\%$ versus $14.0\%$ at 3 hours, $14.1\%$ versus $27.4\%$ at 4 hours, $0\%$ versus $3.3\%$ at 5 hours. Conculsion: Extracorporeal elimination of phosphamidon is effective by hemoperfusio and hemodialysis in vitro. We suggest hemoperfusion may be effective in organophsphate intoxication patients.
- All Author(s)
- 홍세용
; 길효욱
; 양종오
; 이은영
- Issued Date
- 2005
- Type
- Article
- Keyword
- Phosphamidon; Hemoperfusion; Hemodialysis
- Publisher
- 대한임상독성학회
- ISSN
- 1738-1320
- Citation Title
- 대한임상독성학회지
Journal of the Korean Society of Clinical Toxicology
- Citation Volume
- 3
- Citation Number
- 1
- Citation Start Page
- 17
- Citation End Page
- 21
- Language(ISO)
- kor
- URI
- http://schca-ir.schmc.ac.kr/handle/2022.oak/577
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